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Nano-Delivery Of Coconut Oil Compound Could Be Safer Acne Treatment

March 17, 2010: 09:59 AM EST
Lauric acid, found in both coconut oil and human breast milk, shows potential as a safer treatment for acne when carried by tiny "nano-bombs" to skin bacteria sites, new US research shows. The natural substance has a side benefit: it avoids the objectionable side effects like burning and inflammation of current acne treatments. Researchers developed a nano-scale delivery system that carries tiny lauric-acid-filled bubbles straight to acne-causing bacteria in the skin. Gold nanoparticles attached to the surfaces of the lauric-acid-filled nano-bombs (liposomes) prevent them from fusing and point them toward the acne-causing bacteria. When the liposomes reach the bacterial membranes, the gold nanoparticles drop off, freeing the liposomes to do their deadly work. Next step? "These nano-bombs are likely to be tested on humans in the near future," a researcher says.
Dissaya Pornpattananangkul, Sage Olson, Santosh Aryal, et al., "Stimuli-Responsive Liposome Fusion Mediated by Gold Nanoparticles", ACS Nano, March 17, 2010, © American Chemical Society
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